Hematology · LIVE

NCI CTC v2.0 radiation mucositis

NCI CTC mucositis

Apply NCI CTC v2.0 Mucositis due to radiation (Trotti 2000; CTC 30 April 1999) and return grade 0–4 from a caller-assigned mucosal appearance token. magent does not examine the mucosa.

LIVE $0.005 USDC GET /api/calc/nci_ctc_mucositis

Markdown: /docs/nci-ctc-mucositis.md · Canonical: https://magentlab.com/docs/nci-ctc-mucositis

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply NCI CTC v2.0 Mucositis due to radiation (Trotti 2000; CTC 30 April 1999) and return grade 0–4 from a caller-assigned mucosal appearance token. magent does not examine the mucosa.

When to use

When an agent already has a caller-assigned NCI CTC v2.0 radiation mucositis appearance (none, erythema, patchy_pseudomembrane, confluent_pseudomembrane, or necrosis_or_deep_ulcer) and needs the published grade. Not CTC stomatitis/pharyngitis (chemotherapy oral mucositis), not CTCAE v3/v4/v5, and not WHO mucositis.

When not to use

• Not a medical device.
• Not a diagnosis. magent does not examine the mucosa. The caller assigns appearance.
• NCI CTC v2.0 Mucositis due to radiation (30 April 1999) only. Not CTC stomatitis or pharyngitis (chemotherapy oral mucositis) grades.
• Not CTCAE v3, v4, or v5 mucositis.
• Not WHO mucositis.
• Grade 5 (death related to toxicity) is not a token. This tool maps appearance to grades 0–4 only.

Formula

nci_ctc_mucositis appearance none → grade 0; erythema → 1 (erythema of the mucosa); patchy_pseudomembrane → 2 (patchy pseudomembranous reaction, patches generally ≤1.5 cm and noncontiguous); confluent_pseudomembrane → 3 (confluent pseudomembranous reaction, contiguous patches generally >1.5 cm); necrosis_or_deep_ulcer → 4 (necrosis or deep ulceration; may include bleeding not induced by minor trauma or abrasion) (NCI CTC v2.0 Mucositis due to radiation; Trotti 2000). Not CTC stomatitis/pharyngitis. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis

Citation

Title

Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy

Authors

Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morrisintegral M, Rich T, Shipley W, Curran W

Source

Int J Radiat Oncol Biol Phys. 2000;47(1):13-47

DOI

10.1016/s0360-3016(99)00559-3

Worked example

Also searched as

• NCI CTC mucositis
• CTC v2.0 mucositis due to radiation
• radiation mucositis grade
• NCI Common Toxicity Criteria mucositis
• Trotti 2000 CTC
• CTC radiation mucositis
• pseudomembranous mucositis
• NCI CTC v2 mucositis

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/nci_ctc_mucositis?appearance=erythema

Full URL: https://api.magentlab.com/api/calc/nci_ctc_mucositis?appearance=erythema

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/nci_ctc_mucositis?appearance=erythema"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/nci_ctc_mucositis Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "appearance": "erythema"
    },
    {
      "appearance": "erythema"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/nci_ctc_mucositis",
  "items": [
    {
      "description": "Erythema of the mucosa",
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morrisintegral M, Rich T, Shipley W, Curran W",
        "doi": "10.1016/s0360-3016(99)00559-3",
        "id": "trotti-2000",
        "pmid": "10758303",
        "source": "Int J Radiat Oncol Biol Phys. 2000;47(1):13-47",
        "title": "Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy"
      },
      "formula": "nci_ctc_mucositis",
      "formula_expression": "nci_ctc_mucositis appearance none → grade 0; erythema → 1 (erythema of the mucosa); patchy_pseudomembrane → 2 (patchy pseudomembranous reaction, patches generally ≤1.5 cm and noncontiguous); confluent_pseudomembrane → 3 (confluent pseudomembranous reaction, contiguous patches generally >1.5 cm); necrosis_or_deep_ulcer → 4 (necrosis or deep ulceration; may include bleeding not induced by minor trauma or abrasion) (NCI CTC v2.0 Mucositis due to radiation; Trotti 2000). Not CTC stomatitis/pharyngitis. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis",
      "criteria": [
        {
          "factor": "none",
          "met": false
        },
        {
          "factor": "erythema",
          "met": true
        },
        {
          "factor": "patchy_pseudomembrane",
          "met": false
        },
        {
          "factor": "confluent_pseudomembrane",
          "met": false
        },
        {
          "factor": "necrosis_or_deep_ulcer",
          "met": false
        }
      ],
      "grade": 1,
      "appearance": "erythema"
    },
    {
      "description": "Erythema of the mucosa",
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morrisintegral M, Rich T, Shipley W, Curran W",
        "doi": "10.1016/s0360-3016(99)00559-3",
        "id": "trotti-2000",
        "pmid": "10758303",
        "source": "Int J Radiat Oncol Biol Phys. 2000;47(1):13-47",
        "title": "Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy"
      },
      "formula": "nci_ctc_mucositis",
      "formula_expression": "nci_ctc_mucositis appearance none → grade 0; erythema → 1 (erythema of the mucosa); patchy_pseudomembrane → 2 (patchy pseudomembranous reaction, patches generally ≤1.5 cm and noncontiguous); confluent_pseudomembrane → 3 (confluent pseudomembranous reaction, contiguous patches generally >1.5 cm); necrosis_or_deep_ulcer → 4 (necrosis or deep ulceration; may include bleeding not induced by minor trauma or abrasion) (NCI CTC v2.0 Mucositis due to radiation; Trotti 2000). Not CTC stomatitis/pharyngitis. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis",
      "criteria": [
        {
          "factor": "none",
          "met": false
        },
        {
          "factor": "erythema",
          "met": true
        },
        {
          "factor": "patchy_pseudomembrane",
          "met": false
        },
        {
          "factor": "confluent_pseudomembrane",
          "met": false
        },
        {
          "factor": "necrosis_or_deep_ulcer",
          "met": false
        }
      ],
      "grade": 1,
      "appearance": "erythema"
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "description": "Erythema of the mucosa",
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morrisintegral M, Rich T, Shipley W, Curran W",
    "doi": "10.1016/s0360-3016(99)00559-3",
    "id": "trotti-2000",
    "pmid": "10758303",
    "source": "Int J Radiat Oncol Biol Phys. 2000;47(1):13-47",
    "title": "Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy"
  },
  "formula": "nci_ctc_mucositis",
  "formula_expression": "nci_ctc_mucositis appearance none → grade 0; erythema → 1 (erythema of the mucosa); patchy_pseudomembrane → 2 (patchy pseudomembranous reaction, patches generally ≤1.5 cm and noncontiguous); confluent_pseudomembrane → 3 (confluent pseudomembranous reaction, contiguous patches generally >1.5 cm); necrosis_or_deep_ulcer → 4 (necrosis or deep ulceration; may include bleeding not induced by minor trauma or abrasion) (NCI CTC v2.0 Mucositis due to radiation; Trotti 2000). Not CTC stomatitis/pharyngitis. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis",
  "criteria": [
    {
      "factor": "none",
      "met": false
    },
    {
      "factor": "erythema",
      "met": true
    },
    {
      "factor": "patchy_pseudomembrane",
      "met": false
    },
    {
      "factor": "confluent_pseudomembrane",
      "met": false
    },
    {
      "factor": "necrosis_or_deep_ulcer",
      "met": false
    }
  ],
  "grade": 1,
  "appearance": "erythema"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• ASTCT CRS — Apply Lee 2019 ASTCT Table 1 cytokine release syndrome grading and return grade 0–4 from caller-assigned fever, fever waiver, hypotension, and hypoxia. Grade is the more severe of hypotension versus hypoxia. Organ toxicities do not influence grade. Not ICANS.
• TDN Grade — Apply the Terrapon 2021 Therapy-Disability-Neurology grade and return tdn_grade 1-5 as the maximum of caller-assigned therapy, mapped mRS disability, and new-deficit neurology grades.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.