Hematology · LIVE

Plasma starting dose

Compute the BSH Green 2018 starting plasma volume from body weight: 15 mL/kg in the absence of major bleeding. Adult starting dose only.

LIVE $0.005 USDC GET /api/calc/plasma_dosage

Markdown: /docs/plasma-dosage.md · Canonical: https://magentlab.com/docs/plasma-dosage

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute the BSH Green 2018 starting plasma volume from body weight: 15 mL/kg in the absence of major bleeding. Adult starting dose only.

When to use

When an agent needs the published adult starting plasma volume and must not invent a major-haemorrhage RBC:plasma ratio, a cryoprecipitate pool, a paediatric variant, or a product or ABO-group choice.

When not to use

• Not a medical device. Not a transfusion order.
• Not a major-haemorrhage protocol. Does not implement RBC:plasma ratios, cryoprecipitate pools, or paediatric variants. Adult starting 15 mL/kg only.
• magent does not choose a product or ABO group.

Formula

volume_ml = 15 * weight_kg

Citation

Title

Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding

Authors

Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology

Source

Br J Haematol. 2018;181(1):54-67

DOI

10.1111/bjh.15167

Worked example

Also searched as

• plasma starting dose
• plasma 15 ml per kg
• BSH plasma volume
• Green 2018 plasma
• adult plasma starting volume
• plasma dosage
• starting plasma volume

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/plasma_dosage?weight_kg=70

Full URL: https://api.magentlab.com/api/calc/plasma_dosage?weight_kg=70

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/plasma_dosage?weight_kg=70"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/plasma_dosage Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "weight_kg": "70"
    },
    {
      "weight_kg": "70"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/plasma_dosage",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology",
        "doi": "10.1111/bjh.15167",
        "id": "green-2018",
        "pmid": "29524364",
        "source": "Br J Haematol. 2018;181(1):54-67",
        "title": "Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding"
      },
      "formula": "plasma_dosage",
      "formula_expression": "volume_ml = 15 * weight_kg",
      "volume_ml": 1050.0,
      "weight_kg": 70.0,
      "ml_per_kg": 15
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology",
        "doi": "10.1111/bjh.15167",
        "id": "green-2018",
        "pmid": "29524364",
        "source": "Br J Haematol. 2018;181(1):54-67",
        "title": "Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding"
      },
      "formula": "plasma_dosage",
      "formula_expression": "volume_ml = 15 * weight_kg",
      "volume_ml": 1050.0,
      "weight_kg": 70.0,
      "ml_per_kg": 15
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S; British Society for Haematology",
    "doi": "10.1111/bjh.15167",
    "id": "green-2018",
    "pmid": "29524364",
    "source": "Br J Haematol. 2018;181(1):54-67",
    "title": "Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding"
  },
  "formula": "plasma_dosage",
  "formula_expression": "volume_ml = 15 * weight_kg",
  "volume_ml": 1050.0,
  "weight_kg": 70.0,
  "ml_per_kg": 15
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• Allowable blood loss — Compute Gross 1983 dilution-corrected allowable blood loss from a caller-supplied estimated blood volume and initial versus target hematocrit.
• Kaplan plasma volume — Compute Kaplan 1990 estimated plasma volume for therapeutic plasma exchange from weight and hematocrit as a percent, returning one plasma volume in liters and milliliters.
• Ganzoni iron deficit — Compute the Ganzoni 1970 iron deficit from weight, measured hemoglobin, a caller-supplied target hemoglobin, and depot iron stores.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.