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NCI CTC v2.0 stomatitis/pharyngitis

NCI CTC stomatitis

Apply NCI CTC v2.0 Stomatitis/pharyngitis (oral/pharyngeal mucositis) (Trotti 2000; CTC 30 April 1999) and return grade 0–4 from a caller-assigned oral/pharyngeal appearance token. magent does not examine the mucosa.

LIVE $0.005 USDC GET /api/calc/nci_ctc_stomatitis

Markdown: /docs/nci-ctc-stomatitis.md · Canonical: https://magentlab.com/docs/nci-ctc-stomatitis

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply NCI CTC v2.0 Stomatitis/pharyngitis (oral/pharyngeal mucositis) (Trotti 2000; CTC 30 April 1999) and return grade 0–4 from a caller-assigned oral/pharyngeal appearance token. magent does not examine the mucosa.

When to use

When an agent already has a caller-assigned NCI CTC v2.0 stomatitis/pharyngitis appearance (none, painless_or_mild_soreness, painful_can_eat, painful_cannot_eat, or parenteral_or_prophylactic_intubation) and needs the published grade. Not NCI CTC v2.0 Mucositis due to radiation (use nci-ctc-mucositis), not CTCAE v4/v5 as a full catalog, and not WHO mucositis.

When not to use

• Not a medical device.
• Not a diagnosis. magent does not examine the mucosa. The caller assigns appearance.
• NCI CTC v2.0 Stomatitis/pharyngitis (oral/pharyngeal mucositis, 30 April 1999) only. Not NCI CTC v2.0 Mucositis due to radiation (use nci-ctc-mucositis).
• Not CTCAE v4 or v5 as a full catalog.
• Not WHO mucositis.
• Grade 5 (death related to toxicity) is not a token. This tool maps appearance to grades 0–4 only.

Formula

nci_ctc_stomatitis appearance none → grade 0; painless_or_mild_soreness → 1 (painless ulcers, erythema, or mild soreness in the absence of lesions); painful_can_eat → 2 (painful erythema, edema or ulcers, but can eat or swallow); painful_cannot_eat → 3 (painful erythema, edema or ulcers, and cannot eat or swallow); parenteral_or_prophylactic_intubation → 4 (severe ulceration or requires parenteral or enteral support or prophylactic intubation) (NCI CTC v2.0 Stomatitis/pharyngitis (oral/pharyngeal mucositis); Trotti 2000). Not CTC Mucositis due to radiation. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis

Citation

Title

Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy

Authors

Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morris M, Rich T, Shipley W, Curran W

Source

Int J Radiat Oncol Biol Phys. 2000;47(1):13-47

DOI

10.1016/s0360-3016(99)00559-3

Worked example

Also searched as

• NCI CTC stomatitis
• CTC v2.0 stomatitis/pharyngitis
• oral mucositis grade
• NCI Common Toxicity Criteria stomatitis
• Trotti 2000 CTC stomatitis
• chemotherapy stomatitis grade
• oral/pharyngeal mucositis
• NCI CTC v2 stomatitis

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/nci_ctc_stomatitis?appearance=painless_or_mild_soreness

Full URL: https://api.magentlab.com/api/calc/nci_ctc_stomatitis?appearance=painless_or_mild_soreness

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/nci_ctc_stomatitis?appearance=painless_or_mild_soreness"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/nci_ctc_stomatitis Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "appearance": "painless_or_mild_soreness"
    },
    {
      "appearance": "painless_or_mild_soreness"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/nci_ctc_stomatitis",
  "items": [
    {
      "description": "Painless ulcers, erythema, or mild soreness in the absence of lesions",
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morris M, Rich T, Shipley W, Curran W",
        "doi": "10.1016/s0360-3016(99)00559-3",
        "id": "trotti-2000",
        "pmid": "10758303",
        "source": "Int J Radiat Oncol Biol Phys. 2000;47(1):13-47",
        "title": "Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy"
      },
      "formula": "nci_ctc_stomatitis",
      "formula_expression": "nci_ctc_stomatitis appearance none → grade 0; painless_or_mild_soreness → 1 (painless ulcers, erythema, or mild soreness in the absence of lesions); painful_can_eat → 2 (painful erythema, edema or ulcers, but can eat or swallow); painful_cannot_eat → 3 (painful erythema, edema or ulcers, and cannot eat or swallow); parenteral_or_prophylactic_intubation → 4 (severe ulceration or requires parenteral or enteral support or prophylactic intubation) (NCI CTC v2.0 Stomatitis/pharyngitis (oral/pharyngeal mucositis); Trotti 2000). Not CTC Mucositis due to radiation. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis",
      "criteria": [
        {
          "factor": "none",
          "met": false
        },
        {
          "factor": "painless_or_mild_soreness",
          "met": true
        },
        {
          "factor": "painful_can_eat",
          "met": false
        },
        {
          "factor": "painful_cannot_eat",
          "met": false
        },
        {
          "factor": "parenteral_or_prophylactic_intubation",
          "met": false
        }
      ],
      "grade": 1,
      "appearance": "painless_or_mild_soreness"
    },
    {
      "description": "Painless ulcers, erythema, or mild soreness in the absence of lesions",
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morris M, Rich T, Shipley W, Curran W",
        "doi": "10.1016/s0360-3016(99)00559-3",
        "id": "trotti-2000",
        "pmid": "10758303",
        "source": "Int J Radiat Oncol Biol Phys. 2000;47(1):13-47",
        "title": "Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy"
      },
      "formula": "nci_ctc_stomatitis",
      "formula_expression": "nci_ctc_stomatitis appearance none → grade 0; painless_or_mild_soreness → 1 (painless ulcers, erythema, or mild soreness in the absence of lesions); painful_can_eat → 2 (painful erythema, edema or ulcers, but can eat or swallow); painful_cannot_eat → 3 (painful erythema, edema or ulcers, and cannot eat or swallow); parenteral_or_prophylactic_intubation → 4 (severe ulceration or requires parenteral or enteral support or prophylactic intubation) (NCI CTC v2.0 Stomatitis/pharyngitis (oral/pharyngeal mucositis); Trotti 2000). Not CTC Mucositis due to radiation. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis",
      "criteria": [
        {
          "factor": "none",
          "met": false
        },
        {
          "factor": "painless_or_mild_soreness",
          "met": true
        },
        {
          "factor": "painful_can_eat",
          "met": false
        },
        {
          "factor": "painful_cannot_eat",
          "met": false
        },
        {
          "factor": "parenteral_or_prophylactic_intubation",
          "met": false
        }
      ],
      "grade": 1,
      "appearance": "painless_or_mild_soreness"
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "description": "Painless ulcers, erythema, or mild soreness in the absence of lesions",
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Trotti A, Byhardt R, Stetz J, Gwede C, Corn B, Fu K, Gunderson L, McCormick B, Morris M, Rich T, Shipley W, Curran W",
    "doi": "10.1016/s0360-3016(99)00559-3",
    "id": "trotti-2000",
    "pmid": "10758303",
    "source": "Int J Radiat Oncol Biol Phys. 2000;47(1):13-47",
    "title": "Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy"
  },
  "formula": "nci_ctc_stomatitis",
  "formula_expression": "nci_ctc_stomatitis appearance none → grade 0; painless_or_mild_soreness → 1 (painless ulcers, erythema, or mild soreness in the absence of lesions); painful_can_eat → 2 (painful erythema, edema or ulcers, but can eat or swallow); painful_cannot_eat → 3 (painful erythema, edema or ulcers, and cannot eat or swallow); parenteral_or_prophylactic_intubation → 4 (severe ulceration or requires parenteral or enteral support or prophylactic intubation) (NCI CTC v2.0 Stomatitis/pharyngitis (oral/pharyngeal mucositis); Trotti 2000). Not CTC Mucositis due to radiation. Not CTCAE. Not WHO mucositis. magent does not examine the mucosa. Not a diagnosis",
  "criteria": [
    {
      "factor": "none",
      "met": false
    },
    {
      "factor": "painless_or_mild_soreness",
      "met": true
    },
    {
      "factor": "painful_can_eat",
      "met": false
    },
    {
      "factor": "painful_cannot_eat",
      "met": false
    },
    {
      "factor": "parenteral_or_prophylactic_intubation",
      "met": false
    }
  ],
  "grade": 1,
  "appearance": "painless_or_mild_soreness"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• NCI CTC mucositis — Apply NCI CTC v2.0 Mucositis due to radiation (Trotti 2000; CTC 30 April 1999) and return grade 0–4 from a caller-assigned mucosal appearance token. magent does not examine the mucosa.
• ASTCT CRS — Apply Lee 2019 ASTCT Table 1 cytokine release syndrome grading and return grade 0–4 from caller-assigned fever, fever waiver, hypotension, and hypoxia. Grade is the more severe of hypotension versus hypoxia. Organ toxicities do not influence grade. Not ICANS.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.