Liver · LIVE

mRECIST for HCC

mRECIST

Apply Lencioni 2010 modified RECIST (mRECIST) for hepatocellular carcinoma and return target-lesion overall response CR, PR, SD, or PD from caller-assigned viable-tumor flags.

LIVE $0.005 USDC GET /api/calc/mrecist

Markdown: /docs/mrecist.md · Canonical: https://magentlab.com/docs/mrecist

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Apply Lencioni 2010 modified RECIST (mRECIST) for hepatocellular carcinoma and return target-lesion overall response CR, PR, SD, or PD from caller-assigned viable-tumor flags.

When to use

When an agent already has caller-assigned flags for new lesions, disappearance of intratumoral arterial enhancement in all target lesions, a 30% or greater viable-sum reduction versus baseline, and a 20% or greater viable-sum increase versus nadir, and needs the published first-match mRECIST category. magent does not measure arterial-phase enhancement or read CT/MRI.

When not to use

• Not a medical device.
• Not a diagnosis. Response category is not an HCC diagnosis or a treatment recommendation.
• HCC target-lesion mRECIST only (Lencioni 2010 typical intrahepatic target lesions).
• Not RECIST 1.1. Unidimensional viable (arterial-enhancing) tumor is scored; conventional RECIST 1.1 longest-diameter rules are out of scope.
• magent does not read imaging or measure arterial-phase enhancement. All flags are caller-assigned.
• Not nontarget-only overall response. This tool does not combine a separate nontarget-lesion category with target-lesion response.
• Not EASL necrosis-only criteria.
• Does not apply the 2019 Llovet J Hepatol 5 mm absolute increase as an extra PD requirement (a later RECIST-style refinement). viable_sum_increase_ge_20 is the 20% or greater viable-sum increase versus nadir as assigned by the caller.

Formula

mrecist first-match: PD if new_lesion or viable_sum_increase_ge_20; else CR if enhancement_disappeared; else PR if viable_sum_reduction_ge_30; else SD (Lencioni 2010 typical intrahepatic target lesions). Not RECIST 1.1. Not EASL necrosis-only. Not the 2019 Llovet +5 mm PD refinement. magent does not read imaging. Not a diagnosis

Citation

Title

Modified RECIST (mRECIST) assessment for hepatocellular carcinoma

Authors

Lencioni R, Llovet JM

Source

Semin Liver Dis. 2010;30(1):52-60

DOI

10.1055/s-0030-1247132

Worked example

Also searched as

• mRECIST
• modified RECIST HCC
• Lencioni 2010 mRECIST
• HCC arterial enhancement response
• viable tumor RECIST
• modified RECIST hepatocellular carcinoma
• mRECIST CR PR SD PD
• HCC target lesion response

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/mrecist?new_lesion=false&viable_sum_increase_ge_20=false&enhancement_disappeared=true&viable_sum_reduction_ge_30=false

Full URL: https://api.magentlab.com/api/calc/mrecist?new_lesion=false&viable_sum_increase_ge_20=false&enhancement_disappeared=true&viable_sum_reduction_ge_30=false

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/mrecist?new_lesion=false&viable_sum_increase_ge_20=false&enhancement_disappeared=true&viable_sum_reduction_ge_30=false"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/mrecist Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "enhancement_disappeared": "true",
      "new_lesion": "false",
      "viable_sum_increase_ge_20": "false",
      "viable_sum_reduction_ge_30": "false"
    },
    {
      "enhancement_disappeared": "true",
      "new_lesion": "false",
      "viable_sum_increase_ge_20": "false",
      "viable_sum_reduction_ge_30": "false"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/mrecist",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Lencioni R, Llovet JM",
        "doi": "10.1055/s-0030-1247132",
        "id": "lencioni-2010",
        "pmid": "20175033",
        "source": "Semin Liver Dis. 2010;30(1):52-60",
        "title": "Modified RECIST (mRECIST) assessment for hepatocellular carcinoma"
      },
      "formula": "mrecist",
      "formula_expression": "mrecist first-match: PD if new_lesion or viable_sum_increase_ge_20; else CR if enhancement_disappeared; else PR if viable_sum_reduction_ge_30; else SD (Lencioni 2010 typical intrahepatic target lesions). Not RECIST 1.1. Not EASL necrosis-only. Not the 2019 Llovet +5 mm PD refinement. magent does not read imaging. Not a diagnosis",
      "criteria": [
        {
          "factor": "new_lesion",
          "met": false
        },
        {
          "factor": "viable_sum_increase_ge_20",
          "met": false
        },
        {
          "factor": "enhancement_disappeared",
          "met": true
        },
        {
          "factor": "viable_sum_reduction_ge_30",
          "met": false
        }
      ],
      "mrecist": "CR"
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Lencioni R, Llovet JM",
        "doi": "10.1055/s-0030-1247132",
        "id": "lencioni-2010",
        "pmid": "20175033",
        "source": "Semin Liver Dis. 2010;30(1):52-60",
        "title": "Modified RECIST (mRECIST) assessment for hepatocellular carcinoma"
      },
      "formula": "mrecist",
      "formula_expression": "mrecist first-match: PD if new_lesion or viable_sum_increase_ge_20; else CR if enhancement_disappeared; else PR if viable_sum_reduction_ge_30; else SD (Lencioni 2010 typical intrahepatic target lesions). Not RECIST 1.1. Not EASL necrosis-only. Not the 2019 Llovet +5 mm PD refinement. magent does not read imaging. Not a diagnosis",
      "criteria": [
        {
          "factor": "new_lesion",
          "met": false
        },
        {
          "factor": "viable_sum_increase_ge_20",
          "met": false
        },
        {
          "factor": "enhancement_disappeared",
          "met": true
        },
        {
          "factor": "viable_sum_reduction_ge_30",
          "met": false
        }
      ],
      "mrecist": "CR"
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Lencioni R, Llovet JM",
    "doi": "10.1055/s-0030-1247132",
    "id": "lencioni-2010",
    "pmid": "20175033",
    "source": "Semin Liver Dis. 2010;30(1):52-60",
    "title": "Modified RECIST (mRECIST) assessment for hepatocellular carcinoma"
  },
  "formula": "mrecist",
  "formula_expression": "mrecist first-match: PD if new_lesion or viable_sum_increase_ge_20; else CR if enhancement_disappeared; else PR if viable_sum_reduction_ge_30; else SD (Lencioni 2010 typical intrahepatic target lesions). Not RECIST 1.1. Not EASL necrosis-only. Not the 2019 Llovet +5 mm PD refinement. magent does not read imaging. Not a diagnosis",
  "criteria": [
    {
      "factor": "new_lesion",
      "met": false
    },
    {
      "factor": "viable_sum_increase_ge_20",
      "met": false
    },
    {
      "factor": "enhancement_disappeared",
      "met": true
    },
    {
      "factor": "viable_sum_reduction_ge_30",
      "met": false
    }
  ],
  "mrecist": "CR"
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

Related tools

• BCLC — Apply Reig 2022 BCLC staging and return bclc_stage (0, A, B, C, or D) with the published expected median survival. Stage only. Not a treatment recommendation.
• Milan — Apply Mazzaferro 1996 Milan criteria and return whether the published size, count, vascular-invasion, and extrahepatic rules all hold (meets_milan).

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.