Hemodynamics · LIVE
SAVE-score (Schmidt 2015)
SAVE-score
Sum Schmidt 2015 Table 4 SAVE-score cells including the published constant −6 and return class I–V with hospital survival percents.
Markdown: /docs/save.md · Canonical: https://magentlab.com/docs/save
Not a medical device. Not a diagnosis, dose, or listing recommendation.
What it computes
Sum Schmidt 2015 Table 4 SAVE-score cells including the published constant −6 and return class I–V with hospital survival percents.
When to use
When an agent has caller-assigned pre-ECMO Table 4 predictors and needs the published integer SAVE-score and class, not a cannulation order and not Chen 2016 modified SAVE.
When not to use
- Not a medical device. magent does not assign VA-ECMO, does not cannulate, and does not examine the patient.
- Not a cannulation order, eCPR protocol, or futility determination. Derivation excluded ECMO during CPR.
- Schmidt 2015 Table 4 only, plus the published constant −6. Not Chen 2016 modified SAVE (no lactate cell). Not RESP (VV-ECMO).
- Diagnoses and acute pre-ECMO organ failures may stack (Table 4: select one or more). Other diagnoses score 0. Acute and chronic renal failure are separate cells.
- A score of 0 is approximately 50% hospital survival in the paper text; this tool returns the Table 4 class percent (I 75, II 58, III 42, IV 30, V 18), not a continuous logit.
- Organ-failure flags, PIP, blood pressure, pulse pressure, and bicarbonate are caller-assigned. magent does not measure labs or airway pressure.
Formula
SAVE = constant(−6) + age(18–38 → 7, 39–52 → 4, 53–62 → 3, ≥63 → 0) + weight_kg(≤65 → 1, 66–89 → 2, ≥90 → 0) + myocarditis(3) + refractory_vt_vf(2) + post_heart_or_lung_transplant(3) + congenital_heart_disease(−3) + liver_failure(−3) + cns_dysfunction(−3) + acute_renal_failure(−3) + chronic_renal_failure(−6) + intubation_hours(≤10 → 0, 11–29 → −2, ≥30 → −4) + pip_cmh2o(≤20 → 3) + pre_ecmo_cardiac_arrest(−2) + diastolic_bp_mm_hg(≥40 → 3) + pulse_pressure_mm_hg(≤20 → −2) + bicarbonate_mmol_l(≤15 → −3); diagnoses and acute organ failures may stack (Table 4 select one or more); other diagnoses 0; range −35 to 17; class I >5 → 75%, II 1–5 → 58%, III −4 to 0 → 42%, IV −9 to −5 → 30%, V ≤−10 → 18%
Citation
- Authors
- Schmidt M, Burrell A, Roberts L, et al.
- Source
- Eur Heart J. 2015;36(33):2246-2256
Worked example
Offset-only adult row (constant −6, no other Table 4 cells)
Given:
acute_renal_failure=falseage=70bicarbonate_mmol_l=24chronic_renal_failure=falsecns_dysfunction=falsecongenital_heart_disease=falsediastolic_bp_mm_hg=35intubation_hours=5liver_failure=falsemyocarditis=falsepip_cmh2o=25post_heart_or_lung_transplant=falsepre_ecmo_cardiac_arrest=falsepulse_pressure_mm_hg=40refractory_vt_vf=falseweight_kg=95
- Age ≥63 → 0; weight ≥90 → 0; no diagnosis flags → 0; no organ-failure flags → 0
- Intubation ≤10 → 0; PIP >20 → 0; no arrest → 0; DBP <40 → 0; pulse pressure >20 → 0; HCO3 >15 → 0
- Constant −6 on every row
- Score = −6; class IV (−9 to −5); hospital_survival_percent 30
Younger age, myocarditis, and other Table 4 protective cells
Given:
acute_renal_failure=falseage=30bicarbonate_mmol_l=24chronic_renal_failure=falsecns_dysfunction=falsecongenital_heart_disease=falsediastolic_bp_mm_hg=45intubation_hours=5liver_failure=falsemyocarditis=truepip_cmh2o=18post_heart_or_lung_transplant=falsepre_ecmo_cardiac_arrest=falsepulse_pressure_mm_hg=40refractory_vt_vf=falseweight_kg=70
- Age 18–38 → 7; weight 66–89 → 2; myocarditis → 3; PIP ≤20 → 3; DBP ≥40 → 3
- No stacked forbidden cells; congenital false; no risk cells
- Constant −6
- Score = 7+2+3+3+3−6 = 12; class I; hospital_survival_percent 75
Also searched as
- SAVE score
- SAVE-score
- survival after VA-ECMO
- Schmidt SAVE
- veno-arterial ECMO survival
- hospital survival after ECMO
- VA-ECMO SAVE
Try
Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.
Full URL: https://api.magentlab.com/api/calc/save?age=70&weight_kg=95&myocarditis=false&refractory_vt_vf=false&post_heart_or_lung_transplant=false&congenital_heart_disease=false&liver_failure=false&cns_dysfunction=false´_renal_failure=false&chronic_renal_failure=false&intubation_hours=5&pip_cmh2o=25&pre_ecmo_cardiac_arrest=false&diastolic_bp_mm_hg=35&pulse_pressure_mm_hg=40&bicarbonate_mmol_l=24
Call
Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params
return HTTP 400 before any quote or charge.
curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/save?age=70&weight_kg=95&myocarditis=false&refractory_vt_vf=false&post_heart_or_lung_transplant=false&congenital_heart_disease=false&liver_failure=false&cns_dysfunction=false´_renal_failure=false&chronic_renal_failure=false&intubation_hours=5&pip_cmh2o=25&pre_ecmo_cardiac_arrest=false&diastolic_bp_mm_hg=35&pulse_pressure_mm_hg=40&bicarbonate_mmol_l=24"
Parameters
| Name | Type | Required | Description |
|---|---|---|---|
age |
integer | required | Age in years (18-120). Schmidt 2015 Table 4: 18–38 → 7, 39–52 → 4, 53–62 → 3, ≥63 → 0. Adult SAVE-score; magent does not assign pediatric VA-ECMO. |
weight_kg |
number | required | Weight in kg (20-400). Table 4 / Table 3 bands: ≤65 → 1, 66–89 → 2, ≥90 → 0. 65 kg scores 1 (≤65 before the 65–89 typeset overlap). Caller-supplied; magent does not weigh the patient. |
myocarditis |
boolean | required | Acute myocarditis diagnosis (Table 4, +3). Diagnoses are not mutually exclusive (select one or more). true or false. Caller-assigned. |
refractory_vt_vf |
boolean | required | Refractory ventricular tachycardia or fibrillation (Table 4, +2). May stack with other diagnosis flags. true or false. Caller-assigned. |
post_heart_or_lung_transplant |
boolean | required | Post heart or lung transplantation (Table 4, +3). May stack with other diagnosis flags. true or false. Caller-assigned. |
congenital_heart_disease |
boolean | required | Congenital heart disease (Table 4, −3). May stack with other diagnosis flags. true or false. Caller-assigned. |
liver_failure |
boolean | required | Acute pre-ECMO liver failure (Table 4, −3). Paper footnote: bilirubin ≥33 µmol/L or ALT or AST >70 U/L. Acute organ failures may stack. true or false. Caller-assigned; magent does not measure labs. |
cns_dysfunction |
boolean | required | Acute pre-ECMO CNS dysfunction (Table 4, −3): neurotrauma, stroke, encephalopathy, cerebral embolism, seizure or epileptic syndromes. May stack. true or false. Caller-assigned; magent does not examine the patient. |
acute_renal_failure |
boolean | required | Acute pre-ECMO renal failure (Table 4, −3): creatinine >1.5 mg/dL with or without RRT. Distinct from chronic_renal_failure. May stack. true or false. Caller-assigned. |
chronic_renal_failure |
boolean | required | Chronic renal failure (Table 4, −6): kidney damage or GFR <60 mL/min/1.73 m² for ≥3 months. Distinct from acute_renal_failure. true or false. Caller-assigned. |
intubation_hours |
number | required | Hours of intubation before ECMO (0-720). Table 4: ≤10 → 0, 11–29 → −2, ≥30 → −4. Caller-supplied; magent does not read a ventilator log. |
pip_cmh2o |
number | required | Peak inspiratory pressure in cmH2O (5-80). Table 4: ≤20 → +3, otherwise 0. Worst value as assigned by the caller. magent does not read airway pressure. |
pre_ecmo_cardiac_arrest |
boolean | required | Cardiac arrest before ECMO (Table 4, −2). Derivation excluded eCPR during cannulation. true or false. Caller-assigned. |
diastolic_bp_mm_hg |
number | required | Diastolic blood pressure in mm Hg before ECMO (1-200). Worst value within 6 h of cannulation. Table 4: ≥40 → +3, otherwise 0. magent does not measure blood pressure. |
pulse_pressure_mm_hg |
number | required | Pulse pressure in mm Hg before ECMO (0-200). Worst value within 6 h. Table 4: ≤20 → −2, otherwise 0. Caller-supplied; magent does not subtract systolic minus diastolic. |
bicarbonate_mmol_l |
number | required | Serum bicarbonate in mmol/L before ECMO (1-50). Worst value within 6 h. Table 4: ≤15 → −3, otherwise 0. magent does not measure HCO3. |
Bulk (POST)
POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.
- 1 to 25 items. Each item uses the same keys as the GET query parameters.
- POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
- The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
- HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
- Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
- x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.
Example request (fixture)
{
"items": [
{
"acute_renal_failure": "false",
"age": "70",
"bicarbonate_mmol_l": "24",
"chronic_renal_failure": "false",
"cns_dysfunction": "false",
"congenital_heart_disease": "false",
"diastolic_bp_mm_hg": "35",
"intubation_hours": "5",
"liver_failure": "false",
"myocarditis": "false",
"pip_cmh2o": "25",
"post_heart_or_lung_transplant": "false",
"pre_ecmo_cardiac_arrest": "false",
"pulse_pressure_mm_hg": "40",
"refractory_vt_vf": "false",
"weight_kg": "95"
},
{
"acute_renal_failure": "false",
"age": "70",
"bicarbonate_mmol_l": "24",
"chronic_renal_failure": "false",
"cns_dysfunction": "false",
"congenital_heart_disease": "false",
"diastolic_bp_mm_hg": "35",
"intubation_hours": "5",
"liver_failure": "false",
"myocarditis": "false",
"pip_cmh2o": "25",
"post_heart_or_lung_transplant": "false",
"pre_ecmo_cardiac_arrest": "false",
"pulse_pressure_mm_hg": "40",
"refractory_vt_vf": "false",
"weight_kg": "95"
}
]
}
Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.
Example 200 (fixture)
{
"count": 2,
"path": "/api/calc/save",
"items": [
{
"components": [
{
"factor": "myocarditis",
"points": 0,
"present": false
},
{
"factor": "refractory_vt_vf",
"points": 0,
"present": false
},
{
"factor": "post_heart_or_lung_transplant",
"points": 0,
"present": false
},
{
"factor": "congenital_heart_disease",
"points": 0,
"present": false
},
{
"value": 70,
"factor": "age",
"points": 0,
"present": false
},
{
"value": 95.0,
"factor": "weight_kg",
"points": 0,
"present": false
},
{
"factor": "liver_failure",
"points": 0,
"present": false
},
{
"factor": "cns_dysfunction",
"points": 0,
"present": false
},
{
"factor": "acute_renal_failure",
"points": 0,
"present": false
},
{
"factor": "chronic_renal_failure",
"points": 0,
"present": false
},
{
"value": 5.0,
"factor": "intubation_hours",
"points": 0,
"present": false
},
{
"value": 25.0,
"factor": "pip_cmh2o",
"points": 0,
"present": false
},
{
"factor": "pre_ecmo_cardiac_arrest",
"points": 0,
"present": false
},
{
"value": 35.0,
"factor": "diastolic_bp_mm_hg",
"points": 0,
"present": false
},
{
"value": 40.0,
"factor": "pulse_pressure_mm_hg",
"points": 0,
"present": false
},
{
"value": 24.0,
"factor": "bicarbonate_mmol_l",
"points": 0,
"present": false
},
{
"factor": "constant",
"points": -6,
"present": true
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Schmidt M, Burrell A, Roberts L, et al.",
"doi": "10.1093/eurheartj/ehv194",
"id": "schmidt-2015",
"pmid": "26033984",
"source": "Eur Heart J. 2015;36(33):2246-2256",
"title": "Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score"
},
"formula": "save",
"formula_expression": "SAVE = constant(−6) + age(18–38 → 7, 39–52 → 4, 53–62 → 3, ≥63 → 0) + weight_kg(≤65 → 1, 66–89 → 2, ≥90 → 0) + myocarditis(3) + refractory_vt_vf(2) + post_heart_or_lung_transplant(3) + congenital_heart_disease(−3) + liver_failure(−3) + cns_dysfunction(−3) + acute_renal_failure(−3) + chronic_renal_failure(−6) + intubation_hours(≤10 → 0, 11–29 → −2, ≥30 → −4) + pip_cmh2o(≤20 → 3) + pre_ecmo_cardiac_arrest(−2) + diastolic_bp_mm_hg(≥40 → 3) + pulse_pressure_mm_hg(≤20 → −2) + bicarbonate_mmol_l(≤15 → −3); diagnoses and acute organ failures may stack (Table 4 select one or more); other diagnoses 0; range −35 to 17; class I >5 → 75%, II 1–5 → 58%, III −4 to 0 → 42%, IV −9 to −5 → 30%, V ≤−10 → 18%",
"max_score": 17,
"score": -6,
"min_score": -35,
"hospital_survival_percent": 30,
"save_class": "IV"
},
{
"components": [
{
"factor": "myocarditis",
"points": 0,
"present": false
},
{
"factor": "refractory_vt_vf",
"points": 0,
"present": false
},
{
"factor": "post_heart_or_lung_transplant",
"points": 0,
"present": false
},
{
"factor": "congenital_heart_disease",
"points": 0,
"present": false
},
{
"value": 70,
"factor": "age",
"points": 0,
"present": false
},
{
"value": 95.0,
"factor": "weight_kg",
"points": 0,
"present": false
},
{
"factor": "liver_failure",
"points": 0,
"present": false
},
{
"factor": "cns_dysfunction",
"points": 0,
"present": false
},
{
"factor": "acute_renal_failure",
"points": 0,
"present": false
},
{
"factor": "chronic_renal_failure",
"points": 0,
"present": false
},
{
"value": 5.0,
"factor": "intubation_hours",
"points": 0,
"present": false
},
{
"value": 25.0,
"factor": "pip_cmh2o",
"points": 0,
"present": false
},
{
"factor": "pre_ecmo_cardiac_arrest",
"points": 0,
"present": false
},
{
"value": 35.0,
"factor": "diastolic_bp_mm_hg",
"points": 0,
"present": false
},
{
"value": 40.0,
"factor": "pulse_pressure_mm_hg",
"points": 0,
"present": false
},
{
"value": 24.0,
"factor": "bicarbonate_mmol_l",
"points": 0,
"present": false
},
{
"factor": "constant",
"points": -6,
"present": true
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Schmidt M, Burrell A, Roberts L, et al.",
"doi": "10.1093/eurheartj/ehv194",
"id": "schmidt-2015",
"pmid": "26033984",
"source": "Eur Heart J. 2015;36(33):2246-2256",
"title": "Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score"
},
"formula": "save",
"formula_expression": "SAVE = constant(−6) + age(18–38 → 7, 39–52 → 4, 53–62 → 3, ≥63 → 0) + weight_kg(≤65 → 1, 66–89 → 2, ≥90 → 0) + myocarditis(3) + refractory_vt_vf(2) + post_heart_or_lung_transplant(3) + congenital_heart_disease(−3) + liver_failure(−3) + cns_dysfunction(−3) + acute_renal_failure(−3) + chronic_renal_failure(−6) + intubation_hours(≤10 → 0, 11–29 → −2, ≥30 → −4) + pip_cmh2o(≤20 → 3) + pre_ecmo_cardiac_arrest(−2) + diastolic_bp_mm_hg(≥40 → 3) + pulse_pressure_mm_hg(≤20 → −2) + bicarbonate_mmol_l(≤15 → −3); diagnoses and acute organ failures may stack (Table 4 select one or more); other diagnoses 0; range −35 to 17; class I >5 → 75%, II 1–5 → 58%, III −4 to 0 → 42%, IV −9 to −5 → 30%, V ≤−10 → 18%",
"max_score": 17,
"score": -6,
"min_score": -35,
"hospital_survival_percent": 30,
"save_class": "IV"
}
]
}
Response
| Field | Type | Description |
|---|---|---|
formula |
string | save |
formula_expression |
string | Exact expression used |
score |
integer | SAVE-score, theoretical −35 to 17 |
min_score |
integer | -35 |
max_score |
integer | 17 |
save_class |
string | Schmidt 2015 Table 4 class I (>5), II (1–5), III (−4 to 0), IV (−9 to −5), or V (≤−10). A class, not a cannulation order. |
hospital_survival_percent |
integer | Table 4 hospital survival for that class: I 75, II 58, III 42, IV 30, V 18. Score 0 is ~50% in the paper text; this field is the class percent, not a logit. |
components |
array | Per-cell Table 4 points including constant −6 |
citation |
object | Schmidt et al. Eur Heart J 2015 citation |
disclaimer |
string | Not-a-device notice |
Example JSON
Machine form of the same example. Frozen fixture. Not a live lookup.
{
"components": [
{
"factor": "myocarditis",
"points": 0,
"present": false
},
{
"factor": "refractory_vt_vf",
"points": 0,
"present": false
},
{
"factor": "post_heart_or_lung_transplant",
"points": 0,
"present": false
},
{
"factor": "congenital_heart_disease",
"points": 0,
"present": false
},
{
"value": 70,
"factor": "age",
"points": 0,
"present": false
},
{
"value": 95.0,
"factor": "weight_kg",
"points": 0,
"present": false
},
{
"factor": "liver_failure",
"points": 0,
"present": false
},
{
"factor": "cns_dysfunction",
"points": 0,
"present": false
},
{
"factor": "acute_renal_failure",
"points": 0,
"present": false
},
{
"factor": "chronic_renal_failure",
"points": 0,
"present": false
},
{
"value": 5.0,
"factor": "intubation_hours",
"points": 0,
"present": false
},
{
"value": 25.0,
"factor": "pip_cmh2o",
"points": 0,
"present": false
},
{
"factor": "pre_ecmo_cardiac_arrest",
"points": 0,
"present": false
},
{
"value": 35.0,
"factor": "diastolic_bp_mm_hg",
"points": 0,
"present": false
},
{
"value": 40.0,
"factor": "pulse_pressure_mm_hg",
"points": 0,
"present": false
},
{
"value": 24.0,
"factor": "bicarbonate_mmol_l",
"points": 0,
"present": false
},
{
"factor": "constant",
"points": -6,
"present": true
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"citation": {
"authors": "Schmidt M, Burrell A, Roberts L, et al.",
"doi": "10.1093/eurheartj/ehv194",
"id": "schmidt-2015",
"pmid": "26033984",
"source": "Eur Heart J. 2015;36(33):2246-2256",
"title": "Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score"
},
"formula": "save",
"formula_expression": "SAVE = constant(−6) + age(18–38 → 7, 39–52 → 4, 53–62 → 3, ≥63 → 0) + weight_kg(≤65 → 1, 66–89 → 2, ≥90 → 0) + myocarditis(3) + refractory_vt_vf(2) + post_heart_or_lung_transplant(3) + congenital_heart_disease(−3) + liver_failure(−3) + cns_dysfunction(−3) + acute_renal_failure(−3) + chronic_renal_failure(−6) + intubation_hours(≤10 → 0, 11–29 → −2, ≥30 → −4) + pip_cmh2o(≤20 → 3) + pre_ecmo_cardiac_arrest(−2) + diastolic_bp_mm_hg(≥40 → 3) + pulse_pressure_mm_hg(≤20 → −2) + bicarbonate_mmol_l(≤15 → −3); diagnoses and acute organ failures may stack (Table 4 select one or more); other diagnoses 0; range −35 to 17; class I >5 → 75%, II 1–5 → 58%, III −4 to 0 → 42%, IV −9 to −5 → 30%, V ≤−10 → 18%",
"max_score": 17,
"score": -6,
"min_score": -35,
"hospital_survival_percent": 30,
"save_class": "IV"
}
Client errors (HTTP 400)
Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.
| HTTP | Code | When |
|---|---|---|
| 400 | invalid_save |
SAVE needs Schmidt 2015 pre-ECMO cardiogenic-shock predictors in published ranges. Returned before settlement; you are not charged. |
| 400 | invalid_items |
POST body must be a JSON object with only an items array Returned before settlement; you are not charged. |
| 400 | invalid_item_count |
items must be an array of 1 to 25 objects Returned before settlement; you are not charged. |
| 400 | invalid_item |
each items entry must be a JSON object Returned before settlement; you are not charged. |
Related tools
- APACHE II — Compute the Knaus 1985 APACHE II integer from 12 Acute Physiology Score items, age points, and chronic-health points.
- mSOFA — Compute the Grissom 2010 modified SOFA (mSOFA) total from SpO2/FiO2, caller-assigned scleral icterus or jaundice, MAP and adrenergic agents, caller-assigned GCS, and creatinine.
Payment
Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64
PAYMENT-REQUIRED
header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake
and shared payment errors: Payments.
Stdio MCP: /docs/mcp.
Guarantees
- HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
- exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
- HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
- Execution is timeout-bounded and concurrency-capped.
- Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.