Medications · LIVE

Naloxone infusion

Compute a continuous intravenous naloxone infusion rate as two-thirds of the caller-assigned reversal bolus each hour, using the Goldfrank 1986 text rule.

LIVE $0.005 USDC GET /api/calc/naloxone_drip

Markdown: /docs/naloxone-drip.md · Canonical: https://magentlab.com/docs/naloxone-drip

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Compute a continuous intravenous naloxone infusion rate as two-thirds of the caller-assigned reversal bolus each hour, using the Goldfrank 1986 text rule.

When to use

When an agent needs the published Goldfrank 1986 two-thirds infusion from a reversal bolus already given and must not invent a bolus, start naloxone, or look up a nomogram image.

When not to use

• Not a medical device. Deterministic published-formula output only.
• Not a prescription. magent does not name a product, route, concentration, or pump program.
• Not an indication to start naloxone. This tool only converts a reversal bolus the caller already assigned.
• magent does not choose the reversal bolus. reversal_bolus_mg is the bolus already given that resulted in reversal.
• Text rule only. Does not implement a nomogram image or chart lookup.

Formula

infusion_mg_h = (2/3) * reversal_bolus_mg

Citation

Title

A dosing nomogram for continuous infusion intravenous naloxone

Authors

Goldfrank L, Weisman RS, Errick JK, Lo MW

Source

Ann Emerg Med. 1986;15(5):566-570

DOI

10.1016/S0196-0644(86)80994-5

Worked example

Also searched as

• naloxone infusion
• naloxone drip
• continuous naloxone
• Goldfrank naloxone
• naloxone two thirds
• reversal bolus infusion
• IV naloxone infusion

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/naloxone_drip?reversal_bolus_mg=0.4

Full URL: https://api.magentlab.com/api/calc/naloxone_drip?reversal_bolus_mg=0.4

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/naloxone_drip?reversal_bolus_mg=0.4"

Parameters

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/naloxone_drip Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

• 1 to 25 items. Each item uses the same keys as the GET query parameters.
• POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
• The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
• HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
• Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
• x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "reversal_bolus_mg": "0.4"
    },
    {
      "reversal_bolus_mg": "0.4"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/naloxone_drip",
  "items": [
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Goldfrank L, Weisman RS, Errick JK, Lo MW",
        "doi": "10.1016/S0196-0644(86)80994-5",
        "id": "goldfrank-1986",
        "pmid": "3963538",
        "source": "Ann Emerg Med. 1986;15(5):566-570",
        "title": "A dosing nomogram for continuous infusion intravenous naloxone"
      },
      "formula": "goldfrank_1986",
      "formula_expression": "infusion_mg_h = (2/3) * reversal_bolus_mg",
      "infusion_mg_h": 0.267,
      "reversal_bolus_mg": 0.4
    },
    {
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Goldfrank L, Weisman RS, Errick JK, Lo MW",
        "doi": "10.1016/S0196-0644(86)80994-5",
        "id": "goldfrank-1986",
        "pmid": "3963538",
        "source": "Ann Emerg Med. 1986;15(5):566-570",
        "title": "A dosing nomogram for continuous infusion intravenous naloxone"
      },
      "formula": "goldfrank_1986",
      "formula_expression": "infusion_mg_h = (2/3) * reversal_bolus_mg",
      "infusion_mg_h": 0.267,
      "reversal_bolus_mg": 0.4
    }
  ]
}

Response

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Goldfrank L, Weisman RS, Errick JK, Lo MW",
    "doi": "10.1016/S0196-0644(86)80994-5",
    "id": "goldfrank-1986",
    "pmid": "3963538",
    "source": "Ann Emerg Med. 1986;15(5):566-570",
    "title": "A dosing nomogram for continuous infusion intravenous naloxone"
  },
  "formula": "goldfrank_1986",
  "formula_expression": "infusion_mg_h = (2/3) * reversal_bolus_mg",
  "infusion_mg_h": 0.267,
  "reversal_bolus_mg": 0.4
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

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Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

• HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
• exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
• HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
• Execution is timeout-bounded and concurrency-capped.
• Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.