Gleason score (1974)

Gleason score

Sum caller-assigned Gleason 1974 primary and secondary histologic patterns (each 1-5) and return score 2-10. magent does not read slides. Not ISUP/Epstein 2016 Grade Groups.

LIVE $0.005 USDC GET /api/calc/gleason

Markdown: /docs/gleason.md · Canonical: https://magentlab.com/docs/gleason

Not a medical device. Not a diagnosis, dose, or listing recommendation.

What it computes

Sum caller-assigned Gleason 1974 primary and secondary histologic patterns (each 1-5) and return score 2-10. magent does not read slides. Not ISUP/Epstein 2016 Grade Groups.

When to use

When an agent already has caller-assigned Gleason 1974 primary and secondary patterns and needs the published 2-10 sum. magent does not read slides, assign pattern from histology, emit ISUP/Epstein 2016 Grade Groups, or apply 2005 ISUP modified pattern rules.

When not to use

Not a medical device. magent does not read slides.
The caller assigns Gleason 1974 primary and secondary patterns 1-5. magent does not grade glands or inspect architecture.
Gleason 1974 primary-plus-secondary sum only (range 2-10). Not ISUP/Epstein 2016 Grade Groups (1-5). Not 2005 ISUP modified pattern rules.
Gleason 1974 does not name poorly/moderately/well-differentiated score bands on this tool. This tool does not emit those labels.
Not a diagnosis of prostatic adenocarcinoma. Not a treatment or prostatectomy recommendation.

Formula

Gleason score = primary + secondary; each pattern 1-5 as assigned by the caller (Gleason 1974); range 2-10. magent does not read slides. Not ISUP/Epstein 2016 Grade Groups. Not 2005 ISUP modified pattern rules.

Citation

Title: Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging
Authors: Gleason DF, Mellinger GT, Veterans Administration Cooperative Urological Research Group
Source: J Urol. 1974;111(1):58-64
DOI: 10.1016/S0022-5347(17)59889-4

Worked example

Primary 3 secondary 3 is score 6

Given: primary=3secondary=3

primary 3 as assigned by the caller
secondary 3 as assigned by the caller
score = 3 + 3 = 6 (max 10)

Primary 5 secondary 5 is score 10

Given: primary=5secondary=5

primary 5 as assigned by the caller
secondary 5 as assigned by the caller
score = 5 + 5 = 10 (max 10)

Also searched as

Gleason score
Gleason 1974
Gleason pattern
prostatic adenocarcinoma Gleason
Gleason primary secondary
Gleason sum
prostate Gleason score
Gleason histologic grade

Try

Opens the live endpoint. Unpaid browser requests show the paywall; agents should send Accept: application/json.

/api/calc/gleason?primary=3&secondary=3

Full URL: https://api.magentlab.com/api/calc/gleason?primary=3&secondary=3

Call

Expect HTTP 402 until you retry with PAYMENT-SIGNATURE. Incomplete query params return HTTP 400 before any quote or charge.

curl -i -H "Accept: application/json" "https://api.magentlab.com/api/calc/gleason?primary=3&secondary=3"

Parameters

Name	Type	Required	Description
`primary`	integer	required	Caller-assigned Gleason 1974 primary (predominant) histologic pattern. Integer 1-5 only; reject 0, 6, 1.5, and roman I. magent does not read slides or apply 2005 ISUP modified pattern rules.
`secondary`	integer	required	Caller-assigned Gleason 1974 secondary histologic pattern. Integer 1-5 only; reject 0, 6, 1.5, and roman I. magent does not read slides or apply 2005 ISUP modified pattern rules.

Bulk (POST)

POST the same path with a JSON items array. The first item is the GET unit; each additional item is $0.002. Invalid items return HTTP 400 before settlement.

POST /api/calc/gleason Max 25 unit_amount + extra_item_amount * (n - 1) extra $0.002 PREVIEW

1 to 25 items. Each item uses the same keys as the GET query parameters.
POST of 1 item costs the same as GET. Lists longer than 25: chunk into multiple POSTs. Extra items still execute; do not pad dummy rows.
The first invalid item fails the whole request (index in the 400 JSON). You are not charged.
HTTP 200 is {count, path, items}. Each items[i] is the GET 200 body for that row.
Catalog misses (empty matches, found=false) stay paid 200s inside that slot.
x402 resource URL is this path plus n and body_sha256. Browsers that prefer text/html get the same paywall as GET; Pay retries POST with the same items.

Example request (fixture)

{
  "items": [
    {
      "primary": "3",
      "secondary": "3"
    },
    {
      "primary": "3",
      "secondary": "3"
    }
  ]
}

Open bulk paywall →

Opens a two-item fixture on the API host. Unpaid browsers get the same MetaMask paywall as GET; Pay retries POST with those items.

Example 200 (fixture)

{
  "count": 2,
  "path": "/api/calc/gleason",
  "items": [
    {
      "primary": 3,
      "components": [
        {
          "value": 3,
          "factor": "primary",
          "points": 3,
          "present": true
        },
        {
          "value": 3,
          "factor": "secondary",
          "points": 3,
          "present": true
        }
      ],
      "secondary": 3,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Gleason DF, Mellinger GT, Veterans Administration Cooperative Urological Research Group",
        "doi": "10.1016/S0022-5347(17)59889-4",
        "id": "gleason-1974",
        "pmid": "4813554",
        "source": "J Urol. 1974;111(1):58-64",
        "title": "Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging"
      },
      "formula": "gleason",
      "formula_expression": "Gleason score = primary + secondary; each pattern 1-5 as assigned by the caller (Gleason 1974); range 2-10. magent does not read slides. Not ISUP/Epstein 2016 Grade Groups. Not 2005 ISUP modified pattern rules.",
      "max_score": 10,
      "score": 6
    },
    {
      "primary": 3,
      "components": [
        {
          "value": 3,
          "factor": "primary",
          "points": 3,
          "present": true
        },
        {
          "value": 3,
          "factor": "secondary",
          "points": 3,
          "present": true
        }
      ],
      "secondary": 3,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "citation": {
        "authors": "Gleason DF, Mellinger GT, Veterans Administration Cooperative Urological Research Group",
        "doi": "10.1016/S0022-5347(17)59889-4",
        "id": "gleason-1974",
        "pmid": "4813554",
        "source": "J Urol. 1974;111(1):58-64",
        "title": "Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging"
      },
      "formula": "gleason",
      "formula_expression": "Gleason score = primary + secondary; each pattern 1-5 as assigned by the caller (Gleason 1974); range 2-10. magent does not read slides. Not ISUP/Epstein 2016 Grade Groups. Not 2005 ISUP modified pattern rules.",
      "max_score": 10,
      "score": 6
    }
  ]
}

Response

Field	Type	Description
`formula`	string	gleason
`formula_expression`	string	Published Gleason 1974 primary-plus-secondary sum
`primary`	integer	Caller-assigned Gleason 1974 primary pattern 1-5
`secondary`	integer	Caller-assigned Gleason 1974 secondary pattern 1-5
`score`	integer	primary + secondary (range 2-10)
`max_score`	integer	10
`components`	array	Per-pattern Points rows primary and secondary; points equal the integer itself
`citation`	object	Gleason 1974 J Urol citation
`disclaimer`	string	Not-a-device notice

Example JSON

Machine form of the same example. Frozen fixture. Not a live lookup.

{
  "primary": 3,
  "components": [
    {
      "value": 3,
      "factor": "primary",
      "points": 3,
      "present": true
    },
    {
      "value": 3,
      "factor": "secondary",
      "points": 3,
      "present": true
    }
  ],
  "secondary": 3,
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "citation": {
    "authors": "Gleason DF, Mellinger GT, Veterans Administration Cooperative Urological Research Group",
    "doi": "10.1016/S0022-5347(17)59889-4",
    "id": "gleason-1974",
    "pmid": "4813554",
    "source": "J Urol. 1974;111(1):58-64",
    "title": "Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging"
  },
  "formula": "gleason",
  "formula_expression": "Gleason score = primary + secondary; each pattern 1-5 as assigned by the caller (Gleason 1974); range 2-10. magent does not read slides. Not ISUP/Epstein 2016 Grade Groups. Not 2005 ISUP modified pattern rules.",
  "max_score": 10,
  "score": 6
}

Client errors (HTTP 400)

Invalid params return 400 without charge. Shared HTTP 402 and 503 meanings: Payments.

HTTP	Code	When
400	`invalid_gleason`	Gleason score inputs must be caller-assigned pattern integers 1-5 for the two patterns summed in Gleason 1974. Returned before settlement; you are not charged.
400	`invalid_items`	POST body must be a JSON object with only an items array Returned before settlement; you are not charged.
400	`invalid_item_count`	items must be an array of 1 to 25 objects Returned before settlement; you are not charged.
400	`invalid_item`	each items entry must be a JSON object Returned before settlement; you are not charged.

Related tools

Fuhrman — Echo the caller-assigned Fuhrman 1982 nuclear grade (1-4) with the published nuclear-feature description. magent does not read slides. Not WHO/ISUP 2016.
UISS — Apply the Zisman 2002 localized N0M0 three-group UISS algorithm to caller-assigned 1997 pathological T, Fuhrman grade, and ECOG PS and return low_risk, intermediate_risk, or high_risk. Does not compute a predicted 5-year disease-specific survival.

Payment

Unpaid requests return HTTP 402 even if query parameters or POST items are missing or invalid, so CDP and agents can index the path. After a PAYMENT-SIGNATURE, invalid params return HTTP 400 JSON before settlement. magent does not charge. Fix the params, then request a new 402 quote for that complete URL. Catalog misses (empty matches, found=false) are valid paid 200s. Unpaid valid requests return HTTP 402 with a base64 PAYMENT-REQUIRED header. HTTP 503 is not a new quote: retry the same PAYMENT-SIGNATURE. Full handshake and shared payment errors: Payments. Stdio MCP: /docs/mcp.

Guarantees

HTTP 402 is unpaid, including a missing query. After PAYMENT-SIGNATURE, invalid parameters return HTTP 400 before settlement. You are not charged. HTTP 402 never includes the tool JSON.
exact: settlement finishes before the tool (paymentFlow upfront). batch-settlement: verify/deposit before the tool; chargedCumulativeAmount commits after HTTP 2xx. Uncertain or failed settlement fails closed (HTTP 503). Retry the same PAYMENT-SIGNATURE.
HTTP 402 is unpaid only. Do not sign a second authorization because of a 503.
Execution is timeout-bounded and concurrency-capped.
Calculator inputs are stored encrypted for allowlisted operators (Magent Console). They are not in public logs, SSH lookups, catalog, or rollups. Request logs store path without query.